C18 Endcapped Octadecyl

Extracting non-polar compounds  

C18 sorbent is composed of endcapped octadecyl bounded silica gel particles and retains non-polar compounds by hydrophobic interactions. It can retain most organic compounds and is widely used in areas such as environmental monitoring and food safety.

Specifications

1.Carbon content: 17.6%          2.Surface area: 300 m²/g
3.Particle size: 40-75 µm        4.Pore size: 70 Å
– High carbon content
– Fully endcapped surface coverage, reducing interference from basic and pola compounds
– Stable over a broader pH range

Applications

– Analysis of drugs, poisons, pollutants and their metabolites in biological matrices
– Separation of biomolecules such lipids, antibiotics, bile acids and saccharides
– Determination of mycotoxins such as fumonisins in foods
– Determination of preservatives in cosmetics and skin care products 

Related Methods

– GB/T 29598-2013 Limit and determination of triazines in fluorescent brighteners
– GB/T 21323-2007 Determination of aminoglycosides residues in animal tissues —HPLCMS/MS method
– NY/T 1616-2008 Determination of 9 sulfonylurea herbicides residues in soils by LC -MS

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C18 Unendcapped Octadecy

Extracting polar and non-polar compounds     

C18 at organic anlalytes extraction has the broadest spectrum of retention among bonded silica sorbents, since it retains most organic analytes from aqueous matrices, when the compounds of interest vaty widely in structure. Desalting When analyzing small to intermediate molecules, C18 can be used for desalting aqueous matrices prior to ion exchange, as salts pass through the sorbent unretained.

– High carbon content
– Fully endcapped surface coverage, reducing interference from basic and polar compounds
– Stable over a broader pH range

Specifications

1.Carbon content: 17%       2.Surface area: 300 m²/g
3.Particle size: 40-75 µm      4.Pore size: 70 Å

Applications

  – Determination of organic pollutants such as polycyclic aromatic hydrocarbons (PAHs) in soils
– Determination of pesticides and veterinary drugs such as antibiotics in foods
– Analysis of pigments and saccharides in food
– Desalting of aqueous solutions before ion exchange 

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C8 Octyl

Extracting non-polar compounds and neutral compounds were extracted

 C8 sorbent is composed of octyl-bounded silicagel particles and retains non-polar compounds by hydrophobic interactions.
Compared with C18,C8 has shorter carbonchains and moderate hydrophobicity,thus makes an alternative forextracting compounds that are strongly retained by C18 sorbent.

– Moderate hydrophobicity
– Capable of extracting compounds which are strongly retained by C18

Specifications

1.Carbon content: 9%      2.Surface area: 280 m² /g
3.Particle size: 40-75 µm       4.Pore size: 100 Å

Applications                

– Extraction of hydrophilic and lipophilic vitamins in plasma
– Determination of residual hormones in meat
– Determination of residual pesticides in waste
– Desalting of biological macromolecules 

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CN  Cyanopropyl

Extracting polar and non-polar compounds, enriching metal ions

CN is a cyanopropyl bounded silica sorbent, weakly hydrophilic, used as normal phase or reversed phase. It is able to extract non-polar or weakly polar acids, neutrals and bases from aqueous solutions when used as a reversed phase sorbent. It is also able to extract polar compounds from nonpolar organic solutions when used as a normal phase sorbent. Besides, cyanopropyl is a ligand that can be used to enrich some metal ions.

– Compatible with biological matrices
– Polarity adjustable by changing ratio of solvent

Specifications

1.Carbon content: 5.8%            2.Surface area: 480 m² /g
3.Particle size: 40 – 75 µm       4.Pore size: 70 Å

Applications

– Analysis of drugs and drug metabolites (such as steroids) in biological fluids
– Determination of residual pesticides / veterinary drugs in food and milk

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SCCN10006

30

PSA  Primary-Secondary Amine

Extracting strong acids, polar compounds and metal ions

PSA sorbent is similar to NH2 sorbent, offering both normal phase and anion exchange retention mechanisms. Owing to the existence of primary and secondary amino groups (with pKa values 10.1 and 10.9, respectively), PSA has higher ion exchange capabilities and strong hydrogen bonding. Besides, PSA is able to form chelate complexes with some metal ions and used to enrich them.

– Higher capabilities than NH2 sorbent
– Effectively removing acidic interferences in food samples.

 Specifications

1.Carbon content: 8%        2.Surface area: 480 m² /g
3.Particle size: 50 – 75 µm      4.Pore size: 70 Å 

Applications

– Determination of sedatives in body fluids
– Removal of interferences such as fatty acids, organic acids, pigments, sugars and metal ions

Related Methods

– NY/T 468-2006 Determination of residual clenbuterol in animal tissues gas chromatography/mass spectrometry

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NH₂  Aminopropyl

Extracting moderately polar and acidic compounds

Aminopropyl phase, hydrogen bonding and anion exchange. It retains analytes by strongly polar interactions in organic solutions and by weak anion exchange in aqueous solutions.

-Retaining compounds in normal phase or anion exchange mode
-Capable of cleaning up biological samples with complicated matrix components

 Specifications

1.Carbon content: 4.5%       2.Surface area: 480 m² /g
3.Particle size: 40 – 75 µm      4.Pore size: 70 Å

Applications

– Removal of negatively charged species such as sulfuric acids
– Determination of drugs and their metabolites such as β2-adrenergic agonists and salicylic acid in biological fluids (blood and urine)
– Determination of macrolide residues in foods and water

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SAX Strong Anion Exchange

Extracting acidic compounds

SAX is a silica-based strong anion exchanger. Its quaternary ammonium ligand is always positively charged and engenders very strong anion exchange capacity such as carboxylic acids that may not retain strongly enough on PSA or NH_2.

 – Very strong anion exchange interaction with acidic compounds
– Capable of retaining compounds that are not retained weak anion exchange sorbents
– Simple retention mechanism, with minimal secondary interactions

Specifications

1.Surface area: 480 m2 /      2.Particle size: 40 – 75 µm
3.Pore size: 70 Å

Applications

– Removal of negatively charged substances such as organic acids, nucleotides, sulfonic acids and inorganic anions from samples
– Determination of hormones in meat
– Determination of sulfonylurea herbicides in soil,vegetables and cereals

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SCX Strong Cation Exchange

Extracting basic compounds

SCX is a silica-based strong cation exchanger. Its pheylsulfonic acid ligand engenders strong cation exchange capacity, while the benzene ring gives rise to additional non-polar interactions. SCX is able to extract positively charged basic compounds such asamines.

– Low pKa, enabling strong interaction with basic compounds
– Electrical charge of sulfonic acid changeable by adjusting pH of eluent, ensuring convenient elution

 Specifications

1.Surface area: 480 m2 /g      2.Particle size: 40 – 75 µm
3.Pore size: 70 Å

  Applications

– Determination of residual pesticides /veterinary drugs in foodstuff, such as macrolides
-Determination of illicit drugs, such asamphetamine
– Analysis of drugs and drug metabolites in biological Matrices

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